The protesters chanted slogans to condemn Washington’s meddling on Wednesday.
The demonstrators also criticized “US and Israeli domination in the Arab world.”
They demanded the reconstruction of the Yemeni Army and the trial of the former dictator Ali Abdullah Saleh and his associates.
Last week, people took to the streets in the capital city of Sana’a to call for the release of prisoners of the revolution.
Saleh formally stepped down and handed over power to Vice President Abdrabuh Mansur Hadi in February 2012.
The power transfer occurred under a Saudi-backed deal brokered by the (Persian) Gulf Cooperation Council in April 2011 and signed by Saleh in Riyadh on November 23, 2011.
The new Yemeni president, who is a UK-trained field marshal, was sworn in on February 25 following a single-candidate presidential election on February 21, which was supported by the United States and Saudi Arabia.
Since January 2011, Yemenis have held numerous demonstrations across the nation to call for political restructuring of the country and to demand the dismissal of members of Saleh’s regime from their government posts.